Excessive Innate Immunity Steers Pathogenic Adaptive Immunity in the Development of Theiler’s Virus-Induced Demyelinating Disease

Excessive Innate Immunity Steers Pathogenic Adaptive Immunity in the Development of Theiler’s Virus-Induced Demyelinating Disease

Several virus-induced models were used to study the underlying mechanisms of multiple sclerosis (MS). The infection of susceptible mice with Theiler’s murine encephalomyelitis virus (TMEV) establishes persistent viral infections and induces chronic inflammatory demyelinating disease. In this review,...

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Bibliographic Details
Main Author: Byung S. Kim
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
virus
demyelination
inflammation
Th cells
FoxP3<sup>+</sup>CD4<sup>+</sup> T cells
Online Access:https://www.mdpi.com/1422-0067/22/10/5254

Internet

https://www.mdpi.com/1422-0067/22/10/5254

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