Polymorphism of the Dopa-Decarboxylase Gene Modifies the Motor Response to Levodopa in Chinese Patients With Parkinson's Disease

Polymorphism of the Dopa-Decarboxylase Gene Modifies the Motor Response to Levodopa in Chinese Patients With Parkinson's Disease

Levodopa (L-DOPA) is the most effective drug for Parkinson's disease (PD). However, the response to L-DOPA remains individually variable, which hampers the practical value of L-DOPA in the clinic. Genetic factors play a role in L-DOPA efficacy. This study explored the associations between polym...

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Bibliographic Details
Main Authors: Lanting Li, Huixia Lin, Ping Hua, Lei Yan, Hui Dong, Tan Li, Weiguo Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
polymorphisms
DDC
levodopa
motor response
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.520934/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.520934/full

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