Engineering biomimetic periosteum with β-TCP scaffolds to promote bone formation in calvarial defects of rats

Engineering biomimetic periosteum with β-TCP scaffolds to promote bone formation in calvarial defects of rats

Abstract Background There is a critical need for the management of large bone defects. The purpose of this study was to engineer a biomimetic periosteum and to combine this with a macroporous β-tricalcium phosphate (β-TCP) scaffold for bone tissue regeneration. Methods Rat bone marrow-derived mesenc...

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Bibliographic Details
Main Authors: Dan Zhang, Peng Gao, Qin Li, Jinda Li, Xiaojuan Li, Xiaoning Liu, Yunqing Kang, Liling Ren
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Stem Cell Research & Therapy
Subjects:
Biomimetic periosteum
β-TCP
Cell sheet
Critical size defect
Tissue engineering
Online Access:http://link.springer.com/article/10.1186/s13287-017-0592-4

Internet

http://link.springer.com/article/10.1186/s13287-017-0592-4

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