Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs.

The degree to which gene expression covaries between different primary tissues within an individual is not well defined. We hypothesized that expression that is concordant across tissues is more likely influenced by genetic variability than gene expression which is discordant between tissues. We qua...

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Bibliographic Details
Main Authors: Deborah French, Wenjian Yang, Leo H Hamilton, Geoffrey Neale, Yiping Fan, James R Downing, Nancy J Cox, Ching-Hon Pui, William E Evans, Mary V Relling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2374895?pdf=render