Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees.

Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees.

The adaptive immune response to vaccination or infection can lead to the production of specific antibodies to neutralize the pathogen or recruit innate immune effector cells for help. The non-neutralizing role of antibodies in stimulating effector cell responses may have been a key mechanism of the...

Full description

Bibliographic Details
Main Authors: Ickwon Choi, Amy W Chung, Todd J Suscovich, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Jaranit Kaewkungwal, Robert J O'Connell, Donald Francis, Merlin L Robb, Nelson L Michael, Jerome H Kim, Galit Alter, Margaret E Ackerman, Chris Bailey-Kellogg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4395155?pdf=render

Internet

http://europepmc.org/articles/PMC4395155?pdf=render

Similar Items