Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS.

Legionella pneumophila is a facultative intracellular bacterium that lives in aquatic environments where it parasitizes amoeba. However, upon inhalation of contaminated aerosols it can infect and replicate in human alveolar macrophages, which can result in Legionnaires' disease, a severe form o...

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Bibliographic Details
Main Authors: Pascal Ziltener, Thomas Reinheckel, Annette Oxenius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4841525?pdf=render