Co-expression network analysis reveals the pivotal role of mitochondrial dysfunction and interferon signature in juvenile dermatomyositis

Background Juvenile dermatomyositis (JDM) is an immune-mediated disease characterized by chronic organ inflammation. The pathogenic mechanisms remain ill-defined. Methods Raw microarray data of JDM were obtained from the gene expression omnibus (GEO) database. Based on the GSE3307 dataset with 39 sa...

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Bibliographic Details
Main Authors: Danli Zhong, Chanyuan Wu, Jingjing Bai, Dong Xu, Xiaofeng Zeng, Qian Wang
Format: Article
Language:English
Published: PeerJ Inc. 2020-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8611.pdf