Screening of edible mushrooms and extraction by pressurized water (PWE) of 3-hydroxy-3-methyl-glutaryl CoA reductase inhibitors

Screening of edible mushrooms and extraction by pressurized water (PWE) of 3-hydroxy-3-methyl-glutaryl CoA reductase inhibitors

The methanol/water and particularly the water extracts obtained from 26 mushroom species were able to inhibit the 3-hydroxy-3-methyl-glutaryl CoA reductase (HMGCR) activity to different extent (10–76%). Cultivated mushrooms such as Pleurotus sp. and Lentinula edodes were among the strains which show...

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Bibliographic Details
Main Authors: Alicia Gil-Ramírez, Cristina Clavijo, Marimuthu Palanisamy, Alejandro Ruiz-Rodríguez, María Navarro-Rubio, Margarita Pérez, Francisco R. Marín, Guillermo Reglero, Cristina Soler-Rivas
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Functional Foods
Subjects:
Cholesterol
HMGCoA reductase
Pleurotus ostreatus
Lentinus edodes
Accelerated solvent extraction (ASE)
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464612001594

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http://www.sciencedirect.com/science/article/pii/S1756464612001594

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