Incarvillateine produces antinociceptive and motor suppressive effects via adenosine receptor activation.

(-)-Incarvillateine (INCA) is a natural product that has garnered attention due to its purported analgesic effects and historical use as a pain reliever in China. α-Truxillic acid monoesters (TAMEs) constitute a class of inhibitors targeting fatty acid binding protein 5 (FABP5), whose inhibition pro...

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Bibliographic Details
Main Authors: Jinwoo Kim, Diane M Bogdan, Matthew W Elmes, Monaf Awwa, Su Yan, Joyce Che, Garam Lee, Dale G Deutsch, Robert C Rizzo, Martin Kaczocha, Iwao Ojima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218619