Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage

Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage

Apicomplexa generate essential lipids as combination of host fatty acids and de novo synthesized within the apicoplast. Here, the authors identify a phosphatidic acid phosphatase in Toxoplasma gondii, TgLIPIN, as central for controlled lipid synthesis and define the host-scavenged lipidome.

Bibliographic Details
Main Authors: Sheena Dass, Serena Shunmugam, Laurence Berry, Christophe-Sebastien Arnold, Nicholas J. Katris, Samuel Duley, Fabien Pierrel, Marie-France Cesbron-Delauw, Yoshiki Yamaryo-Botté, Cyrille Y. Botté
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22956-w

Internet

https://doi.org/10.1038/s41467-021-22956-w

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