Current Status on Therapeutic Molecules Targeting Siglec Receptors

The sialic acid-binding immunoglobulin-type of lectins (Siglecs) are receptors that recognize sialic acid-containing glycans. In the majority of the cases, Siglecs are expressed on immune cells and play a critical role in regulating immune cell signaling. Over the years, it has been shown that the s...

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Bibliographic Details
Main Authors: María Pia Lenza, Unai Atxabal, Iker Oyenarte, Jesús Jiménez-Barbero, June Ereño-Orbea
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
CAR
Online Access:https://www.mdpi.com/2073-4409/9/12/2691