Dissecting Calcific Aortic Valve Disease—The Role, Etiology, and Drivers of Valvular Fibrosis

Dissecting Calcific Aortic Valve Disease—The Role, Etiology, and Drivers of Valvular Fibrosis

Calcific aortic valve disease (CAVD) is a highly prevalent and progressive disorder that ultimately causes gradual narrowing of the left ventricular outflow orifice with ensuing devastating hemodynamic effects on the heart. Calcific mineral accumulation is the hallmark pathology defining this proces...

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Bibliographic Details
Main Authors: Petra Büttner, Lukas Feistner, Philipp Lurz, Holger Thiele, Joshua D. Hutcheson, Florian Schlotter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
aortic stenosis
CAVD
fibrosis
pathogenesis
myofibroblast
sex differences
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.660797/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.660797/full

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