Verrucarin A Inhibition of MAP Kinase Activation in a PMA-stimulated Promyelocytic Leukemia Cell Line

Verrucarin A Inhibition of MAP Kinase Activation in a PMA-stimulated Promyelocytic Leukemia Cell Line

Abstract: Verrucarin A is an inhibitor of protein synthesis. In this study, we examined the inhibitory action of verrucarin A on signal molecules. Verrucarin A partially inhibited the IL-8 production of a PMA-stimulated promyelocytic leukemia cell line (HL-60 cells), and the effect was related to th...

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Bibliographic Details
Main Authors: Tadashi Kasahara, Yoshio Honma, Hisayoshi Kobayashi, Kyoko Akano, Michio Namikoshi, Taiko Oda
Format: Article
Language:English
Published: MDPI AG 2005-06-01
Series:Marine Drugs
Subjects:
verrucarin A
MAP kinase
HL-60
p38-phosphorylation
JNKphosphorylation
Online Access:http://www.mdpi.com/1660-3397/3/2/64/

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http://www.mdpi.com/1660-3397/3/2/64/

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