Role of TG2-Mediated SERCA2 Serotonylation on Hypoxic Pulmonary Vein Remodeling
Sarco-endoplasmic reticulum Ca2+ ATPase (SERCA) pumps take up Ca2+ from the cytoplasm to maintain the balance of intracellular Ca2+. A decline in expression or activity of SERCA results in persistent store-operated calcium entry (SOCE). In cardiomyocytes as well as vascular smooth muscle cells (SMCs...
Main Authors: | Bo Liu, Dong Wang, Erfei Luo, Jiantong Hou, Yong Qiao, Gaoliang Yan, Qingjie Wang, Chengchun Tang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-02-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphar.2019.01611/full |
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