Glycan recognition in globally dominant human rotaviruses

Glycan recognition in globally dominant human rotaviruses

Human rotaviruses (RV) bind to histo-blood group antigens (HBGA) for attachment, but how different viral genotypes interact with HBGA isn’t known. Here, Hu et al. report crystal structures of a prevalent and a neonate-specific RV in complex with HBGA and provide insights into glycan recognition and...

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Bibliographic Details
Main Authors: Liya Hu, Banumathi Sankaran, Daniel R. Laucirica, Ketki Patil, Wilhelm Salmen, Allan Chris M Ferreon, Phoebe S. Tsoi, Yi Lasanajak, David F. Smith, Sasirekha Ramani, Robert L. Atmar, Mary K. Estes, Josephine C. Ferreon, B. V. Venkataram Prasad
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05098-4

Internet

https://doi.org/10.1038/s41467-018-05098-4

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