P-selectin blockade ameliorates lupus nephritis in MRL/lpr mice through improving renal hypoxia and evaluation using BOLD-MRI

P-selectin blockade ameliorates lupus nephritis in MRL/lpr mice through improving renal hypoxia and evaluation using BOLD-MRI

Abstract Background Lupus nephritis is one of the most common and severe complications of systemic lupus erythematosus, of which poor prognosis is indicated by aggravated renal hypoxia and tubulointerstitial fibrosis. Cell adhesion molecules play a key role in the progression of lupus nephritis tubu...

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Bibliographic Details
Main Authors: Liwen Zhang, Sheng Chen, Yan Liu, Xueqin Xu, Qianying Zhang, Shuxin Shao, Weiming Wang, Xiao Li
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Translational Medicine
Subjects:
Lupus nephritis
Hypoxic
Tubulointerstitial fibrosis
BOLD-MRI
Online Access:http://link.springer.com/article/10.1186/s12967-020-02284-1

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http://link.springer.com/article/10.1186/s12967-020-02284-1

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