Analysis of the DosR regulon genes to select cytotoxic T lymphocyte epitope specific vaccine candidates using a reverse vaccinology approach

Analysis of the DosR regulon genes to select cytotoxic T lymphocyte epitope specific vaccine candidates using a reverse vaccinology approach

Objective/background: There is an urgent need for a more effective vaccine against Mycobacterium tuberculosis (Mtb). Although CD4+ T cells play a central role in host immunity to Mtb, recent evidence suggests a critical role of CD8+ T cells in combating Mtb. In the present study, we have predicted H...

Full description

Bibliographic Details
Main Authors: Kirti Pandey, Monika Sharma, Iti Saarav, Swati Singh, Prasun Dutta, Anshu Bhardwaj, Sadhna Sharma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:International Journal of Mycobacteriology
Subjects:
Cellular immunity
CD8+ T cell epitopes
DosR operon
Mycobacterium tuberculosis
TB vaccines
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=1;spage=34;epage=43;aulast=Pandey

Internet

http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=1;spage=34;epage=43;aulast=Pandey

Similar Items