A computational study of VEGF production by patterned retinal epithelial cell colonies as a model for neovascular macular degeneration

A computational study of VEGF production by patterned retinal epithelial cell colonies as a model for neovascular macular degeneration

Abstract Background The configuration of necrotic areas within the retinal pigmented epithelium is an important element in the progression of age-related macular degeneration (AMD). In the exudative (wet) and non-exudative (dry) forms of the disease, retinal pigment epithelial (RPE) cells respond to...

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Bibliographic Details
Main Authors: Qanita Bani Baker, Gregory J. Podgorski, Elizabeth Vargis, Nicholas S. Flann
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Journal of Biological Engineering
Subjects:
Micropatterning
Auto-regulation
Vascular endothelial growth factor
Age-related macular degeneration
Retinal pigment epithelial cells
Online Access:http://link.springer.com/article/10.1186/s13036-017-0063-6

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http://link.springer.com/article/10.1186/s13036-017-0063-6

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