The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

The Notch signaling pathway is thought to regulate multiple stages of inner ear development. Mutations in the Notch signaling pathway cause disruptions in the number and arrangement of hair cells and supporting cells in sensory regions of the ear. In this study we identify an insertional mutation in...

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Bibliographic Details
Main Authors: Yalda Moayedi, Martin L Basch, Natasha L Pacheco, Simon S Gao, Rosalie Wang, Wilbur Harrison, Ningna Xiao, John S Oghalai, Paul A Overbeek, Graeme Mardon, Andrew K Groves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3879212?pdf=render

Internet

http://europepmc.org/articles/PMC3879212?pdf=render

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