Complement Inhibition Targeted to Injury Specific Neoepitopes Attenuates Atherogenesis in Mice

Rationale: Previous studies have indicated an important role for complement in atherosclerosis, a lipid-driven chronic inflammatory disease associated to oxidative stress in the vessel wall. However, it remains unclear how complement is activated in the process of atherogenesis. An accepted general...

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Bibliographic Details
Main Authors: Shen Dai, Fengming Liu, Mi Ren, Zhongnan Qin, Namita Rout, Xiao-Feng Yang, Hong Wang, Stephen Tomlinson, Xuebin Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.731315/full