B cell repopulation kinetics after rituximab treatment in ANCA-associated vasculitides compared to rheumatoid arthritis, and connective tissue diseases: a longitudinal observational study on 120 patients

B cell repopulation kinetics after rituximab treatment in ANCA-associated vasculitides compared to rheumatoid arthritis, and connective tissue diseases: a longitudinal observational study on 120 patients

Abstract Background B cell depletion with rituximab (RTX) is approved for treatment of rheumatoid arthritis (RA) and ANCA-associated vasculitides (AAV). Recently, RTX has been shown to be effective in AAV maintenance therapy, but an optimal RTX treatment schedule is unknown and the time to B cell re...

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Bibliographic Details
Main Authors: Jens Thiel, Marta Rizzi, Marie Engesser, Ann-Kathrin Dufner, Arianna Troilo, Raquel Lorenzetti, Reinhard E. Voll, Nils Venhoff
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Arthritis Research & Therapy
Subjects:
ANCA
B lymphocyte
Rituximab
Repopulation
Hypogammaglobulinemia
Online Access:http://link.springer.com/article/10.1186/s13075-017-1306-0

Internet

http://link.springer.com/article/10.1186/s13075-017-1306-0

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