Acute Myeloid and Lymphoblastic Leukemia Cell Interactions with Endothelial Selectins: Critical Role of PSGL-1, CD44 and CD43

Acute Myeloid and Lymphoblastic Leukemia Cell Interactions with Endothelial Selectins: Critical Role of PSGL-1, CD44 and CD43

Acute myeloid and lymphoblastic leukemia are poor prognosis hematologic malignancies, which disseminate from the bone marrow into the blood. Blast interactions with selectins expressed by vascular endothelium promote the development of drug resistance and leukostasis. While the role of selectins in...

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Bibliographic Details
Main Authors: Caroline Spertini, Bénédicte Baïsse, Marta Bellone, Milica Gikic, Tatiana Smirnova, Olivier Spertini
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
adhesion
acute leukemia
CLA
selectins
selectin ligands
Online Access:https://www.mdpi.com/2072-6694/11/9/1253

Internet

https://www.mdpi.com/2072-6694/11/9/1253

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