Identification of a Human Anti-Alpha-Toxin Monoclonal Antibody Against Staphylococcus aureus Infection

Identification of a Human Anti-Alpha-Toxin Monoclonal Antibody Against Staphylococcus aureus Infection

Staphylococcus aureus is a major pathogenic bacterium that causes a variety of clinical infections. The emergence of multi-drug resistant mechanisms requires novel strategies to mitigate S. aureus infection. Alpha-hemolysin (Hla) is a key virulence factor that is believed to play a significant role...

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Bibliographic Details
Main Authors: Fangjie Liu, Zhangchun Guan, Yu Liu, Jingjing Li, Chenghua Liu, Yaping Gao, Yuanfang Ma, Jiannan Feng, Beifen Shen, Guang Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Microbiology
Subjects:
alpha-toxin
human monoclonal antibody
Staphylococcus aureus
infection disease
epitope mapping
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.692279/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.692279/full

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