Is methemoglobin an inert bystander, biomarker or a mediator of oxidative stress—The example of anemia?

Acute anemia increases the risk for perioperative morbidity and mortality in critically ill patients who experience blood loss and fluid resuscitation (hemodilution). Animal models of acute anemia suggest that neuronal nitric oxide synthase (nNOS)-derived nitric oxide (NO) is adaptive and protects...

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Bibliographic Details
Main Authors: Gregory M.T. Hare, Albert K.Y. Tsui, Jack H. Crawford, Rakesh P. Patel
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231712000183