Transcriptional insights into the CD8+ T cell response in mono-HIV and HCV infection

Abstract Background Disease progression in the absence of therapy varies significantly in mono-HIV and HCV infected individuals. Virus-specific CD8+ T cells play an important role in restricting lentiviral replication and determining the rate of disease progression during HIV and HCV mono- and co-in...

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Bibliographic Details
Main Authors: Si-Yao Li, Zi-Ning Zhang, Yong‑Jun Jiang, Ya‑Jing Fu, Hong Shang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
HIV
HCV
Online Access:http://link.springer.com/article/10.1186/s12967-020-02252-9