Cerulenin blockade of fatty acid synthase reverses hepatic steatosis in ob/ob mice.

Fatty liver or hepatic steatosis is a common health problem associated with abnormal liver function and increased susceptibility to ischemia/reperfusion injury. The objective of this study was to investigate the effect of the fatty acid synthase inhibitor cerulenin on hepatic function in steatotic o...

Full description

Bibliographic Details
Main Authors: Gang Cheng, Arun P Palanisamy, Zachary P Evans, Alton G Sutter, Lan Jin, Inderjit Singh, Harold May, Michael G Schmidt, Kenneth D Chavin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3785413?pdf=render