Doxorubicin-Loaded PEG-PCL-PEG Micelle Using Xenograft Model of Nude Mice: Effect of Multiple Administration of Micelle on the Suppression of Human Breast Cancer

The triblock copolymer is composed of two identical hydrophilic segments: Monomethoxy poly(ethylene glycol) (mPEG) and one hydrophobic segment poly(ε‑caprolactone) (PCL); which is synthesized by coupling of mPEG-PCL-OH and mPEG‑COOH in a mild condition using dicyclohexylcarbodiimide and 4-dimethylam...

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Bibliographic Details
Main Authors: Ming-Fa Hsieh, Shyh-Chuan Jwo, Jim-Ray Chen, Yu-Lun Li, Jian-Lin Jiang, Nguyen-Van Cuong
Format: Article
Language:English
Published: MDPI AG 2010-12-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/1/61/