The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats.

Adenosine, a catabolite of ATP, displays a wide variety of effects in the heart including regulation of cardiac response to myocardial ischemia and reperfusion injury. Nonetheless, the precise mechanism of adenosine-induced cardioprotection is still elusive. Isolated Sprague-Dawley rat hearts underw...

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Bibliographic Details
Main Authors: Lei Sun, Dong-Ling Li, Mei Zhao, Xi He, Xiao-Jiang Yu, Yi Miao, Hao Wang, Jun Ren, Wei-Jin Zang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3208538?pdf=render