Cell Wall Composition Heterogeneity between Single Cells in Aspergillus fumigatus Leads to Heterogeneous Behavior during Antifungal Treatment and Phagocytosis

The fungus Aspergillus fumigatus can cause invasive lung diseases in immunocompromised patients resulting in high mortality. Treatment using antifungal compounds is often unsuccessful. Average population measurements hide what is happening at the individual cell level. We set out to test what impact...

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Bibliographic Details
Main Authors: Robert-Jan Bleichrodt, Peter Foster, Gareth Howell, Jean-Paul Latgé, Nick D. Read
Format: Article
Language:English
Published: American Society for Microbiology 2020-05-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.03015-19