Complex Epigenetic Regulation of Chemotherapy Resistance and Biology in Esophageal Squamous Cell Carcinoma via MicroRNAs

Complex Epigenetic Regulation of Chemotherapy Resistance and Biology in Esophageal Squamous Cell Carcinoma via MicroRNAs

Background: Resistance towards chemotherapy is a major obstacle in the treatment of esophageal squamous cell carcinoma (ESCC). We investigated the role of specific microRNAs in chemotherapy resistance and tumor biology. Methods: We selected three microRNAs from characteristic microRNA signatures of...

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Bibliographic Details
Main Authors: Kirsten Lindner, Ann-Kathrin Eichelmann, Christiane Matuszcak, Damian James Hussey, Jörg Haier, Richard Hummel
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA
esophageal squamous cell carcinoma
chemotherapy
resistance
metastasis
K410: KYSE-410
K270: KYSE-270
miR: miRNA
Online Access:http://www.mdpi.com/1422-0067/19/2/499

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http://www.mdpi.com/1422-0067/19/2/499

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