Development of a combined RLEP/16S rRNA (RT) qPCR assay for the detection of viable M. leprae from nasal swab samples

Development of a combined RLEP/16S rRNA (RT) qPCR assay for the detection of viable M. leprae from nasal swab samples

Abstract Background Leprosy continues to be a health problem in endemic areas. More than 200,000 new cases of leprosy per year suggest that transmission of the disease is still ongoing, presumably as airborne infection through nasal droplets. Late diagnosis supports continued transmission and increa...

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Main Authors: Marcus Beissner, Anna Woestemeier, Malkin Saar, Kossi Badziklou, Issaka Maman, Charlotte Amedifou, Magdalena Wagner, Franz X. Wiedemann, Komi Amekuse, Basile Kobara, Karl-Heinz Herbinger, Abiba Banla Kere, Thomas Löscher, Gisela Bretzel
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Infectious Diseases
Subjects:
Mycobacterium leprae
RLEP qPCR
Bacillary load
16 rRNA RT qPCR
Viability
Nasal swab samples
Online Access:http://link.springer.com/article/10.1186/s12879-019-4349-9

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http://link.springer.com/article/10.1186/s12879-019-4349-9

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