Sensitive and specific peak detection for SELDI-TOF mass spectrometry using a wavelet/neural-network based approach.

SELDI-TOF mass spectrometer's compact size and automated, high throughput design have been attractive to clinical researchers, and the platform has seen steady-use in biomarker studies. Despite new algorithms and preprocessing pipelines that have been developed to address reproducibility issues...

Full description

Bibliographic Details
Main Authors: Vincent A Emanuele, Gitika Panicker, Brian M Gurbaxani, Jin-Mann S Lin, Elizabeth R Unger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3495950?pdf=render