Complement Activation Is Associated With Mortality in Patients With Necrotizing Soft-Tissue Infections—A Prospective Observational Study

Complement Activation Is Associated With Mortality in Patients With Necrotizing Soft-Tissue Infections—A Prospective Observational Study

Aim: We assessed whether different complement factors and complement activation products were associated with poor outcome in patients with necrotizing soft-tissue infection (NSTI).Methods: We conducted a prospective, observational study in an intensive care unit where treatment of NSTI is centraliz...

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Bibliographic Details
Main Authors: Markus Korsholm Kristensen, Marco Bo Hansen, Martin Bruun Madsen, Cecilie Bo Hansen, Katrine Pilely, Ole Hyldegaard, Peter Garred
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
necrotizing fasciitis
soft tissue infection
sepsis
amputation
survival complement activation
immune system
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00017/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00017/full

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