Hereditary nonpolyposis colorectal cancer identification and surveillance of high-risk families Câncer colo-retal hereditário não polipose - Diagnóstico e surgimento de famílias de alto risco

Hereditary nonpolyposis colorectal cancer is an autosomal dominant condition caused by highly penetrant gene mutations. It is characterized by increased susceptibility for a specific group of cancer, mainly colorectal cancer. The syndrome originates from the inheritance of mutations in DNA mismatch...

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Bibliographic Details
Main Authors: Roberta Vasconcelos e Silva, Bernardo Garicochea, Guilherme Cotti, Isabel Cristina Maranho, Raul Cutait
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2005-06-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322005000300011