Airway Epithelial Nucleotide Release Contributes to Mucociliary Clearance

Airway Epithelial Nucleotide Release Contributes to Mucociliary Clearance

Mucociliary clearance (MCC) is a dominant component of pulmonary host defense. In health, the periciliary layer (PCL) is optimally hydrated, thus acting as an efficient lubricant layer over which the mucus layer moves by ciliary force. Airway surface dehydration and production of hyperconcentrated m...

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Bibliographic Details
Main Authors: Catharina van Heusden, Barbara R. Grubb, Brian Button, Eduardo R. Lazarowski
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Life
Subjects:
ATP release
airway epithelia
mucociliary clearance
pannexin 1
vesicular nucleotide transporter
Online Access:https://www.mdpi.com/2075-1729/11/5/430

Internet

https://www.mdpi.com/2075-1729/11/5/430

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