CD71+ Erythroid Cells in Human Neonates Exhibit Immunosuppressive Properties and Compromise Immune Response Against Systemic Infection in Neonatal Mice

CD71+ Erythroid Cells in Human Neonates Exhibit Immunosuppressive Properties and Compromise Immune Response Against Systemic Infection in Neonatal Mice

Newborns are highly susceptible to infectious diseases. The underlying mechanism of neonatal infection susceptibility has generally been related to their under-developed immune system. Nevertheless, this notion has recently been challenged by the discovery of the physiological abundance of immunosup...

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Bibliographic Details
Main Authors: Shokrollah Elahi, Marco Antonio Vega-López, Vladimir Herman-Miguel, Carmen Ramírez-Estudillo, Javier Mancilla-Ramírez, Bruce Motyka, Lori West, Olaide Oyegbami
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
CD71+ erythroid cells
newborns
neonatal infections
immunosuppression
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.597433/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.597433/full

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