Defective Osteogenic Differentiation in the Development of Osteosarcoma

Defective Osteogenic Differentiation in the Development of Osteosarcoma

Osteosarcoma (OS) is associated with poor prognosis due to its high incidence of metastasis and chemoresistance. It often arises in areas of rapid bone growth in long bones during the adolescent growth spurt. Although certain genetic conditions and alterations increase the risk of developing OS, the...

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Bibliographic Details
Main Authors: Eric R. Wagner, Gaurav Luther, Gaohui Zhu, Qing Luo, Qiong Shi, Stephanie H. Kim, Jian-Li Gao, Enyi Huang, Yanhong Gao, Ke Yang, Linyuan Wang, Chad Teven, Xiaoji Luo, Xing Liu, Mi Li, Ning Hu, Yuxi Su, Yang Bi, Bai-Cheng He, Ni Tang, Jinyong Luo, Liang Chen, Guowei Zuo, Richard Rames, Rex C. Haydon, Hue H. Luu, Tong-Chuan He
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2011/325238

Internet

http://dx.doi.org/10.1155/2011/325238

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