Blood DNA methylation signatures to detect dementia prior to overt clinical symptoms

Abstract Introduction This study determined whether blood DNA methylation (DNAm) patterns differentiate individuals with presymptomatic dementia compared to controls. Methods DNAm was measured in 73 individuals prior to dementia diagnosis and 87 cognitively healthy controls matched for age, sex, smo...

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Bibliographic Details
Main Authors: Peter Daniel Fransquet, Paul Lacaze, Richard Saffery, James Phung, Emily Parker, Raj Shah, Anne Murray, Robyn L. Woods, Joanne Ryan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Online Access:https://doi.org/10.1002/dad2.12056