N-Methyl-D-aspartate Induces Phosphorylation of cAMP Response Element (CRE)-Binding Protein and Increases DNA-Binding Activity of CRE in Rat Retina

N-Methyl-D-aspartate Induces Phosphorylation of cAMP Response Element (CRE)-Binding Protein and Increases DNA-Binding Activity of CRE in Rat Retina

The aim of this study was to investigate whether an excitotoxic concentration of N-methyl-D-aspartate (NMDA) increases the expression of the phosphorylated cAMP response element-binding protein (p-CREB) and the DNA-binding activity of the cAMP response element (CRE) in rat retina. Intravitreal injec...

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Bibliographic Details
Main Authors: Kazuyuki Isenoumi, Toshio Kumai, Yasushi Kitaoka, Masamitsu Motoki, Yuka Kitaoka, Kohei Kuribayashi, Yasunari Munemasa, Jiro Kogo, Shinichi Kobayashi, Satoki Ueno
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319324636

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http://www.sciencedirect.com/science/article/pii/S1347861319324636

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