Mutant Allele Frequency-Based Intra-Tumoral Genetic Heterogeneity Related to the Tumor Shrinkage Mode After Neoadjuvant Chemotherapy in Breast Cancer Patients

Mutant Allele Frequency-Based Intra-Tumoral Genetic Heterogeneity Related to the Tumor Shrinkage Mode After Neoadjuvant Chemotherapy in Breast Cancer Patients

The shrinkage mode of tumor extent after neoadjuvant chemotherapy (NAC) is an important index to evaluate the odds of breast-conserving surgery. However, there is no sufficient measurement to predict the shrinkage mode after NAC. In this study, we analyzed 24 patients' formalin-fixed, paraffin-...

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Bibliographic Details
Main Authors: Chun-hui Zheng, Zhao-yun Liu, Chen-xi Yuan, Xiao-yun Dong, Hai-mei Li, Jin-jin Wang, Zhao-peng Zhang, Hong-Ying Liu, Xiao-yan Ding, Wendy Wu, Rui-ru Wang, Yong-sheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Medicine
Subjects:
breast cancer
next generation sequencing
gene heterogeneity
shrinkage mode
neoadjuvant chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.651904/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.651904/full

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