Lithium chloride prevents glucocorticoid-induced osteonecrosis of femoral heads and strengthens mesenchymal stem cell activity in rats

Background:. Accumulating evidence suggests that lithium influences mesenchymal stem cell (MSC) proliferation and osteogenic differentiation. As decreased bone formation in femoral heads is induced by glucocorticoids (GCs), we hypothesized that lithium has a protective effect on GC-induced osteonecr...

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Bibliographic Details
Main Authors: Yue-Lei Zhang, Zhen-Zhong Zhu, Le-Cheng Zhang, Gang Wang, Li-Shao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2021-09-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001530