Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol

Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol

D-Pinitol (DPIN) is a natural occurring inositol capable of activating the insulin pathway in peripheral tissues, whereas this has not been thoroughly studied in the central nervous system. The present study assessed the potential regulatory effects of DPIN on the hypothalamic insulin signaling path...

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Bibliographic Details
Main Authors: Dina Medina-Vera, Juan Antonio Navarro, Rubén Tovar, Cristina Rosell-Valle, Alfonso Gutiérrez-Adan, Juan Carlos Ledesma, Carlos Sanjuan, Francisco Javier Pavón, Elena Baixeras, Fernando Rodríguez de Fonseca, Juan Decara
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nutrients
Subjects:
inositol
D-Pinitol
insulin resistance
hypothalamus
PI3K/Akt pathway
Online Access:https://www.mdpi.com/2072-6643/13/7/2268

Internet

https://www.mdpi.com/2072-6643/13/7/2268

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