Oral Scutellarin Treatment Ameliorates Retinal Thinning and Visual Deficits in Experimental Glaucoma

Purpose: Intraocular pressure (IOP) is currently the only modifiable risk factor for glaucoma, yet glaucoma can continue to progress despite controlled IOP. Thus, development of glaucoma neurotherapeutics remains an unmet need. Scutellarin is a flavonoid that can exert neuroprotective effects in the...

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Main Authors: Jingyuan Zhu, Anoop Sainulabdeen, Krystal Akers, Vishnu Adi, Jeffrey R. Sims, Eva Yarsky, Yi Yan, Yu Yu, Hiroshi Ishikawa, Christopher K. Leung, Gadi Wollstein, Joel S. Schuman, Wenbin Wei, Kevin C. Chan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.681169/full