Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates

Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates

Periodontitis is a chronic inflammatory disease associated with overactivation of the complement system. Recent preclinical studies suggest that host-modulation therapies may contribute to effective treatment of human periodontitis, which may lead to loss of teeth and function if untreated. We previ...

Full description

Bibliographic Details
Main Authors: Tetsuhiro Kajikawa, Ruel A. Briones, Ranillo R.G. Resuello, Joel V. Tuplano, Edimara S. Reis, Evlambia Hajishengallis, Cristina A.G. Garcia, Despina Yancopoulou, John D. Lambris, George Hajishengallis
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
complement
compstatin
periodontitis
inflammation
AMY-101
non-human primates
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050117300906

Internet

http://www.sciencedirect.com/science/article/pii/S2329050117300906

Similar Items