Structural and Functional Insights into Foamy Viral Integrase

Successful integration of retroviral DNA into the host chromosome is an essential step for viral replication. The process is mediated by virally encoded integrase (IN) and orchestrated by 3'-end processing and the strand transfer reaction. In vitro reaction conditions, such as substrate spe...

Full description

Bibliographic Details
Main Authors: Cha-Gyun Shin, Md. Khadem Ali, Md. Alamgir Hossain
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/5/7/1850