Structural and Functional Insights into Foamy Viral Integrase
Successful integration of retroviral DNA into the host chromosome is an essential step for viral replication. The process is mediated by virally encoded integrase (IN) and orchestrated by 3'-end processing and the strand transfer reaction. In vitro reaction conditions, such as substrate spe...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-07-01
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Series: | Viruses |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4915/5/7/1850 |