Grafting TRAIL through either Amino or Carboxylic Groups onto Maghemite Nanoparticles: Influence on Pro-Apoptotic Efficiency

Grafting TRAIL through either Amino or Carboxylic Groups onto Maghemite Nanoparticles: Influence on Pro-Apoptotic Efficiency

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF cytokine superfamily. TRAIL is able to induce apoptosis through engagement of its death receptors DR4 and DR5 in a wide variety of tumor cells while sparing vital normal cells. This makes it a promising agen...

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Bibliographic Details
Main Authors: Hanene Belkahla, Andrei Alexandru Constantinescu, Tijani Gharbi, Florent Barbault, Alexandre Chevillot-Biraud, Philippe Decorse, Olivier Micheau, Miryana Hémadi, Souad Ammar
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Nanomaterials
Subjects:
surface functionalization
maghemite
cell viability
cancer disease
molecular modeling
Online Access:https://www.mdpi.com/2079-4991/11/2/502

Internet

https://www.mdpi.com/2079-4991/11/2/502

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