Substitution of the α-lactalbumin transcription unit by a CAT cDNA within a BAC clone silenced the locus in transgenic mice without affecting the physically linked <it>Cyclin T1 </it>gene

Substitution of the α-lactalbumin transcription unit by a CAT cDNA within a BAC clone silenced the locus in transgenic mice without affecting the physically linked <it>Cyclin T1 </it>gene

<p>Abstract</p> <p>We recently reported that a goat bacterial artificial chromosome (BAC) clone conferred site-independent expression in transgenic mice of the two loci present within its insert, the ubiquitously expressed <it>Cyclin T1 </it>and the mammary specific β-l...

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Bibliographic Details
Main Authors: Jean-Luc Vilotte, Nathalie Besnard, Céline Viglietta, Caroline Maeder, José Da Silva, Marthe Hudrisier, Solange Soulier
Format: Article
Language:deu
Published: BMC 2003-03-01
Series:Genetics Selection Evolution
Subjects:
bacterial artificial chromosome
homologous recombination
intron
transgenic mice
chromatin domain
Online Access:http://www.gsejournal.org/content/35/2/239

Internet

http://www.gsejournal.org/content/35/2/239

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