SIRT1 in the Brain – Connections with Aging-associated Disorders and Lifespan

The silent mating type information regulation 2 proteins (sirtuins) 1 of class III histone deacetylases have been associated with health span and longevity. SIRT1, the best studied member of the mammalian sirtuins, has a myriad of roles in multiple tissues and organs. However, a significant part of...

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Bibliographic Details
Main Authors: Fanny eNg, Laura eWijaya, Bor Luen eTang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00064/full