BpForms and BcForms: a toolkit for concretely describing non-canonical polymers and complexes to facilitate global biochemical networks

Abstract Non-canonical residues, caps, crosslinks, and nicks are important to many functions of DNAs, RNAs, proteins, and complexes. However, we do not fully understand how networks of such non-canonical macromolecules generate behavior. One barrier is our limited formats for describing macromolecul...

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Bibliographic Details
Main Authors: Paul F. Lang, Yassmine Chebaro, Xiaoyue Zheng, John A. P. Sekar, Bilal Shaikh, Darren A. Natale, Jonathan R. Karr
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-020-02025-z