A Prospective Feasibility Trial to Challenge Patient–Derived Pancreatic Cancer Organoids in Predicting Treatment Response

A Prospective Feasibility Trial to Challenge Patient–Derived Pancreatic Cancer Organoids in Predicting Treatment Response

Real-time isolation, propagation, and pharmacotyping of patient-derived pancreatic cancer organoids (PDOs) may enable treatment response prediction and personalization of pancreatic cancer (PC) therapy. In our methodology, PDOs are isolated from 54 patients with suspected or confirmed PC in the fram...

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Bibliographic Details
Main Authors: Alica K. Beutel, Lena Schütte, Jeanette Scheible, Elodie Roger, Martin Müller, Lukas Perkhofer, Annika M. T. U. Kestler, Johann M. Kraus, Hans A. Kestler, Thomas F. E. Barth, Johannes Lemke, Marko Kornmann, Thomas J. Ettrich, Johann Gout, Thomas Seufferlein, Alexander Kleger
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
pancreatic cancer
organoids
drug response prediction
pharmacotyping
personalized medicine
Online Access:https://www.mdpi.com/2072-6694/13/11/2539

Internet

https://www.mdpi.com/2072-6694/13/11/2539

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